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how long do venofer side effects last
Keep out of reach of children. Do not exceed 1,500 mg of iron per dosing course. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Headache. Side effects like nausea and low blood pressure are common with most iron infusions. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. If you have questions about using Injectafer in a child, talk with your doctor. stream This includes people who: Usually, hypophosphatemia doesnt cause symptoms. One study of just under 5000 HRT users found that 43% were affected. Find comprehensive medical information for Venofer intravenous on RxList including its uses, side effects, precautions, drug interactions, overdose, pill images & warnings . You may need extra iron because of blood loss during kidney dialysis. Keep all drugs in a safe place. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. No, you most likely wont take Injectafer long term. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. It belongs to a class of medications called iron replacement products. Before using, check this product visually for particles or discoloration. MNT is the registered trade mark of Healthline Media. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. What are the side effects of Venofer? These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. This treatment course is split into two doses of the drug, which are given at least 7 days apart. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Yes, in some cases it may. Daiichi Sankyo, Inc., the manufacturer of Injectafer, offers a program called injectconnect, which may help lower the cost of the drug. Talk with the doctor. Iron infusion benefits. These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. Together, you and your doctor can discuss the benefits and risks of treatment options for anemia. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. This medication is given by injection into a vein as directed by your doctor. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). % How long does iron infusion stay in your system? Dizziness. Follow all instructions closely. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. Before taking Injectafer, talk with your doctor about your health history. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). Feraheme also comes as a liquid thats given by IV infusion. It belongs to a class of medications known as iron replacement products. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. They have been a god send. Some drugs may have another patient information leaflet. . A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. But for other people, doing so could lead to having too much iron in their body. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. <> If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. They can recommend if this is safe for you to do. Do not flush down a toilet or pour down a drain unless you are told to do so. Talk with your doctor. 2023 Medicine.com All rights reserved. This gives a total cumulative dose of 1,500 mg of Injectafer. On day three I had a headache and felt heavy/exhausted, which lasted a few days. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Injectafer can cause mild or serious side effects. After the infusion, you can drive yourself home and return to your usual activities. People from different ethnic backgrounds process medications differently. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. Potential injection site discoloration has happened. Change in taste. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. Does Venofer Vial interact with other drugs you are taking? But its not known whether this poses any risk to a child whos breastfed. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. For example: Say you weigh 105 pounds (about 48 kilograms). There are different types of anemia, but IDA is the most common type. Its responsible for carrying oxygen throughout your body. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Mental healthdisorders like depression may requireantidepressantsto treat. And these two doses need to be separated by at least 7 days. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. However, some people can experienceside effectsfor much longer - days, months, or indefinitely. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. The study also didnt show if one treatment was worse than the other. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. This is not a complete list of side effects and others may occur. A lack of iron can lead to iron deficiency anaemia if left untreated. Things to remember when you fill your prescription. Nausea. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). But keep in mind that in this study, delayed allergic reaction only occurred in one person. Back pain. However, diarrhea it isnt very common in people using Injectafer. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing This allows them to manage any side effects that you may have following your dose. You can also write a reminder on your calendar. So we cant say for sure whether the drug is safe to use while youre pregnant. But you dont necessarily need to eat these foods unless your doctor tells you to do so. If needed, theyll recommend treatment, including certain medications. Its because everyones body is different. Theseside effectsmay last as long as they are undercancer treatment. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Injectafer isnt available in a generic form. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. Venofer injection contains iron sucrose, a form of the mineral iron. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. No, you wont need to take iron pills while youre using Injectafer. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Following an LSD trip, users may experience a sort of 'comedown.'. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. Vomiting. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. In one study, people were given either Injectafer or an iron replacement drug called Venofer. Hes an expert in genetic testing, genetic analysis, andprecision medicine. With IDA, you have anemia (low red blood cell level) thats due to not having enough iron in your body. Find out what health conditions may be a health risk when taken with Venofer Vial You may wonder how Injectafer compares with other medications that are prescribed for similar uses. This test measures the amount of hemoglobin in your blood. A shortage of iron can cause health problems. (For more information on Venofer, see the Injectafer vs. Venofer section above). Side effectsare uncomfortable reactions to medications or drugs. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. I can't take oral supplements because they cause horrible debilitating Constipation. You may also need to monitor your blood pressure at home. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. There may be drug take-back programs in your area. Low blood pressure. Injectafer and Venofer can cause very similar side effects, but some different ones as well. People with IDA have low blood levels of hemoglobin. Notify your healthcare provider of any irritation at the injection site. Venofer® (iron sucrose injection, USP) is available by prescription only. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. Call your doctor for instructions if you miss an appointment for your Venofer injection. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. Upset stomach or throwing up. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. Learn more about these, as well as the symptoms, diagnosis, and treatments. Hemoglobin is a protein thats found inside your red blood cells. Weight changes may be due to symptoms of anemia improving. Its not known whether its safe to breastfeed while youre taking Injectafer. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. Otherwise, call a poison control center right away. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. fever. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. 4 0 obj Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. I had my first infusion of 1gm 10 days ago. However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. Together, you and your doctor can develop a treatment plan thats best for you. People with IDA have low blood levels of hemoglobin. What is Venofer? Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. Remember that it is best to get your vitamins and minerals from food whenever possible. There have also been reports of serious allergic reactions to Venofer. Joint pain. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. Generics tend to cost less than brand-name drugs. Canada residents can call a provincial poison control center. IQVIA [NSP Audit from MAT November 2013 to November 2018]. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. Learn about the causes, symptoms, diagnosis, and treatment of this. If you have diarrhea while youre taking Injectafer, call your doctor. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. Learn about uses, cost, how it works, and more. Its possible that after getting two doses of Injectafer, your anemia may go away completely. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Instead, youll start by receiving just one treatment course of Injectafer. You may report side effects to Health Canada at 1-866-234-2345. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. Learn how to store and discard medical supplies safely. Others last much longer (even a lifetime), which can be quite traumatizing to people. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. %PDF-1.3 The researchers looked to see how well each drug worked to increase peoples hemoglobin level. Do not exceed 1,500 mg of iron per dosing course. It is given into a vein for a period of time. In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. In Canada - Call your doctor for medical advice about side effects. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. With a delayed reaction, your body reacts to a drug that youve been exposed to in the past without having a reaction. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). Most of these side effects may go away within a few days or a couple of weeks. taste impairment. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. Source: Wolters Kluwer Health. Other drugs are available that can treat iron deficiency anemia (IDA). This medicine may cause serious types . In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. Its not known if Injectafer is safe to use during pregnancy. Here's some detail on certain side effects this drug may cause. As a result, you may not make as much EPO as usual. Serious side effects from Injectafer arent common, but they can occur. They can tell you about other medications that may work well for you. This is not a complete list of side effects and others may occur. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. As with all medications, the cost of Injectafer can vary. To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. endobj Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. weakness. Depending on your anemia symptoms, your weight changes may be different than those described here. Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. Youll receive doses of either drug by a healthcare professional at a medical facility. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. This hormone is made by your kidneys. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. All rights reserved. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. Its caused by your body not having enough iron, which is needed to make hemoglobin. The drug helps increase your hemoglobin level back to a value thats within the normal range. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. You may report side effects to FDA at 1-800-FDA-1088. It is important to get each dose of this medication as scheduled. With anemia, you have a low level of red blood cells (RBCs) in your body. Here we look at how Injectafer and Venofer are alike and different. (Hemoglobin is a protein thats found inside your red blood cells.). }|54U|O~?|_v;f\o^(W+/-|^)O65_)rd sm }[x[)y.z Wz?9_jV0ub,`g`s?oXOSp/Kgw$b!Vb$;IvBVR9n|\0ln=;/=,mgw@do,[";/8nJL{n}Bb-|^6[~>a_1H'^M:^vv=iM+x|+Y . Do not share your drugs with others and do not take anyone else's drugs. They can recommend appropriate treatment options. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or This survey is being conducted by the WebMD marketing sciences department. What is the latest research on the form of cancer Jimmy Carter has? Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. If you have symptoms of a low phosphorus level, call your doctor. Youll receive doses of Injectafer from a healthcare professional at a medical facility. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. Iron infusions are given directly into a vein. Precautions. 2005 - 2023 WebMD LLC. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. HRT, like other medications, does have some side effects and these are thought to be quite common. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. Very bad and sometimes deadly allergic side effects have rarely happened. However, many people have no side effects or only have minor side effects. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. muscle pain. If your symptoms or health problems do not get better or if they become worse, call your doctor. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. . Its not currently available in generic form. If you have questions about side effects, call your doctor. Keep all medications away from children and pets. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. However, be sure to take the dosage your doctor prescribes for you. Injectafer should be stored between 68F to 77F (20C to 25C). You will be watched closely by your doctor for 30 minutes after each dose. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Dizziness. They can give you tips on how to deal with any side effects that may be bothersome. Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. Allergic reactions typically occur the first time your body is exposed to a drug. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. Innovators Monograph reese0809 1 yr. ago. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; The infusion will take between 15-30 minutes if it is given in. With this condition, you also have a low hemoglobin level. But you kidneys need iron in order to make EPO. Venofer Side Effects. reactions at the site of the injection. If either is present, do not use the liquid. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. These people may lose weight as their anemia improves because theyre more active. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. Injectafer is approved to treat iron deficiency anemia (IDA). I had Venofer infusions, 2 rounds now in the span of three years. Talk to your pharmacist for more details.
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